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A recent meta-analysis including data from SURMOUNT-1, a trial conducted in individuals with obesity, confirmed the favorable effects of tirzepatide on dyslipidemia, finding a 16 and 13.7% change from baseline in triglycerides and very low-density lipoproteins with tirzepatide 15 mg vs

(That means GLP-1s supported a 20% boost in the smoking abstinence rate!) When it comes to body weight, the GLP-1 group ended up weighing an average of 5.6 lbs less compared to the placebo group

In patients with T2D, chronic hyperglycaemia, as evidenced by high HbA1c levels, is strongly related to the risk of cardiovascular disease (CVD) and death by inducing oxidative stress and inflammation and promoting atherosclerosis and endothelial dysfunction

Autophagy plays an important role in sunitinib-mediated cell death in H9c2 cardiac muscle cells

Overall, DPP4i, as a class of safe oral hypoglycemic agents, have a role in the management of diabetic patients, and there is extensive experience in their use