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GLP-1 receptor agonists, such as Semaglutide and Tirzepatide, mimic these effects, making them effective for diabetes management

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Importantly, the authors noted that two of the included trials used withdrawal of anti-hypertensive medications as a primary outcome

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The molecular pathways by which mitochondrial derangements act as a unifying pathophysiological link between these conditions are explored in detail, with a particular focus on the oxidative stressinflammation cascade, damage to the vascularneural unit, and systemic metabolic reprogramming