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Apart from inflammation, CSE is inducible by oxidative stress and the CSE promoter harbours a binding site for the master regulator of oxidative stress response, nuclear factor (erythroidderived 2)like 2 (Nrf2) (Martin et al ., 2007

Side effects Because it is the same medicine as the injection, side effects are similar mostly mild-to-moderate gut symptoms (nausea, diarrhoea, constipation) that ease with titration, minus injection-site reactions

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