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10.1016/S0140-6736(19)31271-1 Summary Keywords colorectal cancer, gastrointestinal cancer, GLP-1 receptor agonists, liver cancer, meta-analysis, obesity, oncological safety, pancreatic cancer Citation Wali AF, Rangraze I, Khan S, Mufti UB, El-Tanani M and Rizzo M (2026) Reassessing cancer risk with GLP-1 receptor agonists: a comprehensive meta-analysis of gastrointestinal malignancies

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Relevant considerations: Estrogen decline affects genital tissue health, potentially impacting physical comfort during sex

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GLP-1RAs as a support for MCAS For some basics: glucagon-like peptide-1 receptor agonists (abbreviated as GLP-1 medications or as I noted above, GLP-1RAs) are a class of medications that includes semaglutide (Ozempic/Wegovy) and tirzepatide (Mounjaro/Zepbound, which also work on GIP receptors), as well as in-trials Retatrutide (a triple agonist that works on GLP-1, GIP, and Glucagon receptors)