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The more probable path to "oral tirzepatide" is through a small-molecule dual agonist rather than an oral formulation of the tirzepatide peptide itself

This potential breakthrough is generating excitement as researchers await results from EVOKE and EVOKE+, two global clinical trials studying semaglutide, a GLP-1 drug

The 10mg dose also sits at a pharmacokinetic sweet spot

Animal studies showed developmental abnormalities at clinically relevant doses, but a 2023 multicenter human study of GLP-1 receptor agonist exposure during the first trimester found no elevated risk of major birth defects

Who will monitor your labs and symptoms while you use this medication