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A 2023 randomised controlled trial (RCT) showed that a hypocaloric ketogenic diet was effective in reducing daily glycaemia compared to a low-fat diet, irrespective of weight loss [131]

For hypothyroidism, levothyroxine replacement is recommended

Phosphorylated Smad2 associates with STAT3 to facilitate Th17 cell polarization, whereas unphosphorylated Smad3 interacts with STAT3 to inhibit Th17 cell differentiation

This allows patients to access more flexible treatment options while still utilizing their tax-advantaged savings

L-Carnitine plays a critical role in mitochondrial fatty acid transport, enabling -oxidation of long-chain acyl-CoA substrates and efficient ATP generation from lipid stores