The presence of obesity-related complications such as obstructive sleep apnea, metabolic dysfunction-associated steatotic liver disease (MASLD, formerly NAFLD), or cardiovascular disease may justify longer treatment duration given the health benefits of sustained weight loss
A recent New England Journal of Medicine study showed that although both these new drugs are highly effective, tirzepatide was shown to be more effective for weight loss, possibly because of the combination of these two hormone agonists when compared to the single hormone agonist in semaglutide
Weight Regain and Cardiometabolic Effects After Withdrawal of Semaglutide: The STEP 1 Trial Extension
Slows Gastric Emptying: GLP-1 slows down the rate at which food leaves the stomach
You may be wondering, "how does Wegovy work?" It primarily reduces hunger, helps you feel full sooner when eating, and decreases cravings