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Contributions of bloodbrain barrier imaging to neurovascular unit pathophysiology of Alzheimers disease and related dementias

In preclinical models, Dihexa has shown the ability to increase synaptic markers like synaptophysin, improve neuronal counts in the hippocampus, and restore spatial memory and learning capacity in cognitively impaired animals

10.1016/S0891-5849(02)01009-2

Peptide therapy generally isnt appropriate during pregnancy or breastfeeding, with active or recent cancer, or with certain medical conditions a proper evaluation sorts that out

The TRIUMPH-CVOT readout will not arrive until 2028 or later, but it is the study that ultimately decides whether retatrutide is positioned as a full cardiometabolic compound rather than a weight-loss compound alone